Study to evaluate genetic resistance to HPAI in poultry

Researchers at the University of California, Davis are launching a new study to investigate genetic resistance to highly pathogenic avian influenza (HPAI). The project seeks to identify specific genes and immune pathways that allow certain breeds, such as the Fayoumi heritage chicken, to withstand infection better than modern commercial lines.

By utilizing an embryonated egg model, the team aims to compare these resilient birds against standard broiler and layer stocks. Professor Huaijun Zhou notes that the goal is not to replace current biosecurity or vaccination practices. Instead, this research offers a potential long-term tool to improve animal welfare and mitigate economic losses from future outbreaks.

The findings are intended to support genomic breeding strategies and gene marker-assisted selection for the poultry industry. While this process is not an immediate fix for active outbreaks, it provides a scientific path toward developing more resilient flocks over time. This work is supported by the Foundation for Food & Agriculture Research through its Rapid Outcomes from Agricultural Research program.

Producers and breeders continue to face challenges with avian influenza, and adding genetic resilience to the control portfolio is a key focus for researchers. As the study progresses, the poultry industry will monitor how these genetic insights can be integrated into commercial breeding programs to maintain production sustainability.